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Bronchogen peptide: Metabolic / Longevity research guide

In short: Bronchogen (Ala-Glu-Asp-Leu / AEDL) is a synthetic tetrapeptide from the Khavinson short-peptide family, studied for gene expression and proliferation markers in bronchial epithelial cell cultures. It is studied in preclinical (cell and animal) research and is supplied strictly for laboratory use, not for human or clinical use.

Not medical advice. Bronchogen is a research compound. This guide does not provide dosing, diagnosis, therapy recommendations, or claims about effects in humans.

Bronchogen at a glance

Compound type

Research peptide

Research category

Metabolic / Longevity

Also known as

Bronchogen, AEDL, Ala-Glu-Asp-Leu, H-Ala-Glu-Asp-Leu-OH, alanyl-glutamyl-aspartyl-leucine, Khavinson bronchial bioregulator

Molecular weight

446.46 Da

Evidence context

Preclinical / research use only

Regulatory status

Not an approved medicine. Supplied as a research compound

Last reviewed

13 October 2026

What to know first

Compound Bronchogen Research class Metabolic / Longevity Available pack sizes 10 × 20 mg Storage Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight.

Details and limits sit in the sections below. Research use only. No unsupported scientific claims are added here.

What Bronchogen is

Bronchogen (Ala-Glu-Asp-Leu, "AEDL") is a four-residue synthetic peptide from the Khavinson bioregulator family, studied for gene expression and proliferation markers in bronchial epithelial cell cultures.

One-paragraph overview from our research datasheet. Still scientific, but faster to read than the full mechanism list below.

Bronchogen (Ala-Glu-Asp-Leu / AEDL) is a synthetic tetrapeptide from the Khavinson short-peptide family, studied for gene expression and proliferation markers in bronchial epithelial cell cultures.

Research contexts

Peer-reviewed papers discuss Bronchogen in specific lab settings. The points below reflect research questions, not health claims.

Research vs. personal use: Literature describes experiments in cells and animals. That is distinct from real-world use. Our products are for laboratory research only.

Typical study contexts

Mitochondrial stress, NAD+/redox biology and nutrient-sensing pathways.

Enzyme activity, gene expression or endurance-style animal readouts.

Synthetic Ala-Glu-Asp-Leu (AEDL) tetrapeptide from the Khavinson short-peptide lineage.

Studied in cultured human bronchial epithelial cells for proliferation and apoptosis markers.

Examined for lung-lineage gene expression (NKX2-1, secretoglobins, mucins, surfactant protein A1) in vitro.

DNA-binding profile characterised in cell-free melting and fluorescence assays.

Why Metabolic / Longevity research matters

Researchers study these compounds for mitochondrial function and cellular energy stress. Ageing and metabolic disease models are common.

Mechanisms (technical review)

Our datasheet lists mechanistic themes from preclinical work. These are research endpoints, not health claims.

Synthetic Ala-Glu-Asp-Leu (AEDL) tetrapeptide from the Khavinson short-peptide lineage

Studied in cultured human bronchial epithelial cells for proliferation and apoptosis markers

Examined for lung-lineage gene expression (NKX2-1, secretoglobins, mucins, surfactant protein A1) in vitro

DNA-binding profile characterised in cell-free melting and fluorescence assays

Compared with Epitalon (Ala-Glu-Asp-Gly), which differs only at the last residue

Lab handling & preparation

Storage: Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight.. See the storage guide.

Published pharmacokinetic context: Laboratory research material. No human dosing exists for this compound and none is published or recommended here.

Purity check: Use the COA reading guide and the published Certificates of Analysis (no current certificate is listed for Bronchogen yet).

Common Questions People Are Asking

What is Bronchogen?

Bronchogen is the name used for the synthetic tetrapeptide Ala-Glu-Asp-Leu (AEDL), developed in the Khavinson short-peptide programme and studied in bronchial epithelial cell cultures. It is supplied here as a laboratory research powder only.

Is the sequence AEDL or ADEL?

Most sources, including the patent and the PubChem compound record, give Ala-Glu-Asp-Leu (AEDL). A few papers from the same group print Ala-Asp-Glu-Leu. The composition, formula (C18H30N4O9) and average mass (446.46 Da) are identical either way. This page uses AEDL.

What does the research on Bronchogen show?

In cultured human bronchial epithelial cells it was reported to raise Ki67 and Mcl-1 and lower p53, with larger effects at late passage, and to change lung-lineage gene expression. A rat study reports changes in bronchial epithelium after nitrogen-dioxide exposure. All of it is preclinical and from one research network.

Is there a Certificate of Analysis for Bronchogen?

Not yet. No independent analytical report has been published for this material, so no purity figure is quoted.

Is there human data on Bronchogen?

No human study was found in the literature cited here. Bronchogen is sold strictly for in-vitro and preclinical research, not for human or veterinary use.

Is this page medical advice? Can I use Bronchogen for my health?

No, and no. This article is educational only. We do not provide dosing, medical recommendations, or health claims. Our products are sold strictly for laboratory research, not for personal use of any kind.

Where do I find Bronchogen specs, purity certificates and pricing?

Open the shop listing via “View product details.” There you will see concentration, purity grade, and available SKUs with current pricing. No current Certificate of Analysis is published for Bronchogen yet; published certificates are listed at /coa.

Related peptide guides

Other compounds researchers often read about alongside Bronchogen.

Epitalon: Metabolic / Longevity research guide

Cardiogen: Metabolic / Longevity research guide

Pancragen: Metabolic / Longevity research guide

Vesugen: Metabolic / Longevity research guide

Continue Bronchogen research

Analytical evidence, comparisons and current research for this compound. Research use only.

Research area Cognitive & longevity research The neuropeptide and longevity research area - nootropic and geroprotective peptides and related compounds studied in cognition… Explore the research area →

Scientific sources & further reading

Primary literature and registries for Bronchogen, plus mainstream coverage of the peptide category. Research use only - not medical advice.

Databases & literature:

PubMed: peer-reviewed literature on Bronchogen

ClinicalTrials.gov: registered studies on Bronchogen

Bronchogen: Wikipedia (search)

Peptides in the news:

WebMD: consumer health reference

BBC News: Health

CNN Health: “Peptides: what to know about the wellness trend”

Sky News: “Can peptides make America healthy again?”

Sky News: “Inside the exploding US peptides craze” (video)

Sky News Australia: “Black market peptide trade explodes as influencers fuel uptick in use”

Sky News Australia: “Backyard peptide boom sparks alarm” (video)

Sky News Australia: “Oprah reveals struggle with shame of weight-loss drugs”

Ready to order? View full product specs

Access concentration, batch info, variants, and current pricing on our shop.

Also known as: Bronchogen, AEDL, Ala-Glu-Asp-Leu, H-Ala-Glu-Asp-Leu-OH, alanyl-glutamyl-aspartyl-leucine, Khavinson bronchial bioregulator

PRECISION. PURITY. PERFORMANCE.

Research peptides. Third-party Certificates of Analysis (Janoshik Analytical & Freedom Diagnostics) are published on the website. Supplied strictly for laboratory research use.

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