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Tesamorelin + Ipamorelin Blend
Tesamorelin and ipamorelin in one vial, in three strengths: 5 mg + 5 mg, 10 mg + 4 mg and 10 mg + 5 mg per vial. A GHRH(1-44) analogue paired with a selective ghrelin-receptor agonist.
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Tesamorelin + Ipamorelin Blend
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Lab-direct quality — sealed 10-vial packs
Every batch ships straight from the lab that synthesises it — sealed, tamper-evident. Buying direct means you pay the lab-direct rate on every vial, with nothing stacked on top.
Order a sealed 10-vial research pack in the strength your research needs.
Scientific Research Context
What the published literature on the components of Tesamorelin + Ipamorelin Blend examines. These are findings about each compound in the studies cited, not claims about the blend or the supplied material.
Published tesamorelin trial: HIV-associated abdominal adiposity (the approved medicine, not this material)
In a 26-week randomised, placebo-controlled trial of 412 people with HIV and abdominal fat accumulation, tesamorelin lowered visceral adipose tissue by 15.2% (placebo +5.0%), raised IGF-I by 81% (placebo -5%) and improved triglycerides and the cholesterol to HDL ratio. More people on tesamorelin withdrew for adverse events. [human, tesamorelin alone]
Published tesamorelin trial: HIV and hepatic fat (the approved medicine, not this material)
In 61 people with HIV and fatty liver disease, tesamorelin over 12 months reduced hepatic fat fraction by 4.1 percentage points more than placebo (a 37% relative reduction), with more administration-site complaints in the tesamorelin group. [human, tesamorelin alone]
Ipamorelin: selective GH release
In rat pituitary cells, anaesthetised rats and conscious swine ipamorelin released growth hormone with a potency and efficacy comparable to GHRP-6, without the rise in ACTH and cortisol seen with GHRP-6 and GHRP-2, even at more than 200 times its GH-releasing ED50. [animal and in vitro]
Two different receptors
Antagonist profiling placed ipamorelin's action at a GHRP-like receptor and not the GHRH receptor that tesamorelin targets, which is the reason the pair is of interest to study together. [in vitro and animal]
Overview
In short: A research blend of tesamorelin and ipamorelin in three strengths (5 + 5, 10 + 4 and 10 + 5 mg per vial): a GHRH analogue and a selective ghrelin-receptor agonist in one vial.
Key research facts
These points summarise lab themes, not human outcomes.
Tesamorelin is the better documented half of the pair. It is the 44-residue growth-hormone-releasing hormone sequence with a trans-3-hexenoyl group on the N-terminus, and a 2007 randomised trial in 412 people with HIV and abdominal fat accumulation, followed for 26 weeks, reported a 15.2% fall in visceral adipose tissue against a 5.0% rise on placebo and an 81% rise in IGF-I against a 5% fall. A 2019 trial in 61 people with HIV and fatty liver reported a 4.1-point absolute reduction in hepatic fat fraction at 12 months. Both are studies of tesamorelin alone, in specific patient groups, and neither is evidence about the supplied material or about a blend.
Ipamorelin is a pentapeptide, Aib-His-D-2Nal-D-Phe-Lys-NH2, whose original characterisation in rat pituitary cells, rats and swine found GH release comparable to GHRP-6 with no rise in ACTH or cortisol beyond the GHRH-stimulated level, and an action at a GHRP-like receptor rather than the GHRH receptor. The two compounds therefore engage different receptors on the same cell type.
Unlike the other blends, the ratio here is not constant: TI10 is 5 mg of each, TI14 is 10 mg tesamorelin with 4 mg ipamorelin, and TI15 is 10 mg with 5 mg. No study of the fixed blend is cited. Supplied as lyophilised powder for in-vitro and preclinical research only.
Proposed Mechanism
The blend has no combined mechanism. Tesamorelin is a GHRH-receptor agonist and ipamorelin a ghrelin-type receptor agonist, both acting on pituitary somatotrophs. Pairing them is a hypothesis about two receptors, not a demonstrated property of the vial.
The tesamorelin trials were done in particular patient populations with the approved medicine and say nothing about a laboratory blend, about ipamorelin, or about the other strengths here. The ratio also changes between TI10, TI14 and TI15, so no single composition can be assumed across the menu. When a design needs one compound varied against the other, use the stand-alone tesamorelin and ipamorelin products.
Common Questions People Are Asking
What strengths does the tesamorelin + ipamorelin blend come in?
Three, chosen from the pack-size menu: 10 mg per vial (5 mg tesamorelin + 5 mg ipamorelin, code TI10), 14 mg (10 + 4, TI14) and 15 mg (10 + 5, TI15). The ratio is not the same in each.
Is this the approved tesamorelin medicine?
No. Tesamorelin is the active ingredient of an approved prescription medicine for a specific condition, but the material supplied here is unapproved laboratory research material and is not that product.
Why are tesamorelin and ipamorelin paired?
They act on the same pituitary cell type through different receptors, tesamorelin at the GHRH receptor and ipamorelin at a ghrelin-type receptor. That is the rationale for studying them together. This page cites no study of the fixed blend.
Is there a Certificate of Analysis for this blend?
Not yet. No independent analytical report has been published for this material, so no purity figure is quoted. If one is published it will appear on this page and on our COA page.
Is there human data on this blend?
No study of the blend is cited. The human trials in the references are of tesamorelin alone in specific patient groups. This is laboratory research material, sold strictly for in-vitro and preclinical research and not for human or veterinary use.
Where can I buy Tesamorelin + Ipamorelin Blend?
Right here - Tesamorelin + Ipamorelin Blend is supplied directly by New-U Research Compounds on this page, as lyophilised research-grade material, and shipped direct from source worldwide in discreet, tracked packaging.
How much does Tesamorelin + Ipamorelin Blend cost?
Tesamorelin + Ipamorelin Blend pricing is shown live on this page, per pack size - 10-vial research packs as standard, with single-vial sample options on selected compounds. Shipping is free on orders over $350.
How do I buy Tesamorelin + Ipamorelin Blend?
Add the Tesamorelin + Ipamorelin Blend pack size you need to your cart and check out: enter your shipping details, then choose your payment method - cryptocurrency or card - on the next step.
What payment methods can I use to buy Tesamorelin + Ipamorelin Blend?
At checkout you can pay by card or crypto. New-U supports BTC and selected stablecoin and network-asset payments across Ethereum, Solana, TRON, Polygon, Base, BNB Chain and Linea. You choose your method after confirming your order.
How fast is shipping, and do you ship worldwide?
Yes - we ship worldwide in discreet, unmarked, tracked packaging; lyophilised peptides are stable through the tracked transit window. Delivery typically takes 6–14 business days, and shipping is free on orders over $350.
Is it legal to buy Tesamorelin + Ipamorelin Blend?
In the United States, Tesamorelin + Ipamorelin Blend is sold strictly for laboratory and research purposes only. It is not approved by the FDA for human consumption and is not sold for that purpose. Regulatory status varies by jurisdiction - buyers are responsible for compliance in their own region.
Research use only - all claims made on this site are for testing and research use only.
Pharmacokinetics
Evidence Tier
Overall: Tier 3: Limited / anecdotal
The blend has no evidence base of its own. The human trials cited concern tesamorelin alone in HIV-related settings; ipamorelin has animal and in-vitro pharmacology. No study of the two as a fixed combination is cited. The material is supplied as unapproved laboratory material, not as the approved tesamorelin medicine.
Tier 1 · Human clinical
Tier 2 · Animal
Databases & peer-reviewed sources
Last reviewed: 14 October 2026 · New-U Research Compounds
Key Characteristics
Specifications
About the Tesamorelin + Ipamorelin Blend: Research Guide
Tesamorelin and ipamorelin are both studied for how they drive pituitary growth hormone release, one through the GHRH receptor and the other through a ghrelin-type receptor. A single vial removes a weighing and reconstitution step for studies that call for both, and three strengths let the tesamorelin and ipamorelin amounts follow the design.
Tesamorelin is also the active ingredient of an approved prescription medicine for a specific condition. The material supplied here is laboratory research material and is not that product; the trials in the references are published findings about tesamorelin in those patients and are not claims about this blend or about use in anyone.
New-U Research Compounds supplies this blend as laboratory research material only. No analytical report for it has been published yet, so no purity figure is quoted. Nothing on this page is medical advice.
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Research peptides. Third-party Certificates of Analysis (Janoshik Analytical & Freedom Diagnostics) are published on the website. Supplied strictly for laboratory research use.
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Research use only - all claims made on this site are for testing and research use only. Purchasers must be 21 years of age or older.
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[image: Tesamorelin + Ipamorelin Blend research vial — Stacks compound supplied by New-U Research Compounds]
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